Domenico Caliendo case, consultants: "Dry ice lesions and necrosis on the implanted heart confirmed."

New elements emerge from the evidentiary incident ordered as part of the investigation into the death of little Domenico Caliendo , the two-and-a-half-year-old child who died on February 21st after the failed heart transplant performed at the Monaldi hospital in Naples.

During the latest examination, held at the Institute of Forensic Medicine at the Bari Polyclinic, histological preparations and slides from the transplanted heart were analyzed. According to medical examiner Luca Scognamiglio, a consultant for the Caliendo family, the tests confirmed the presence of lesions consistent with damage caused by transporting the organ using dry ice.

The family consultant's conclusions

"The analysis of the histological samples from the transplanted heart revealed all the evidence supporting tissue necrosis due to exposure of the organ to dry ice," Scognamiglio declared at the conclusion of the expert investigations.

According to the consultant, the microscopic examination confirmed what had already emerged from previous assessments: the implanted heart had arrived in Naples in compromised condition due to exposure to extremely low temperatures during transport.

"All the injuries we would expect to find after transport using dry ice were found," the coroner explained, describing damage similar to actual "cold burns" and tissue alterations consistent with exposure to temperatures much lower than those required for proper organ preservation.

The transplant and the legal case

The story dates back to December 23rd, when Domenico was supposed to receive a new heart transplant. The organ was harvested in Bolzano and transported to Naples.

According to the investigation, the heart was found to be compromised upon arrival at Monaldi Hospital. Meanwhile, however, the child's native heart, suffering from a serious condition, had already been removed.
Since then, a complex medical and legal case has unfolded, culminating in an investigation coordinated by the Naples Public Prosecutor's Office, which aims to clarify any responsibilities in the management of the transport and preservation of the organ destined for transplant.

The effects of long-term use of ECMO

The in-depth studies conducted in Bari didn't focus exclusively on the transplanted heart. The consultants also examined the effects of the long period of extracorporeal membrane oxygenation (ECMO) to which the child was subjected.

According to Scognamiglio, the analyzed samples also revealed "the harmful effects caused by prolonged exposure to ECMO," a circumstance that could be relevant in the clinical reconstruction of the entire affair.

Waiting for the final report

The expert assessment is not yet complete. The panel of experts appointed by Naples investigating judge Mariano Sorrentino has reportedly announced a request for an extension to acquire additional documentation deemed necessary for the final assessment.

The tests will continue over the next few weeks, while we await the final report, which will provide the judge with a definitive picture of the causes of little Domenico's death and the role that the organ transport and subsequent clinical procedures may have played.